Changes in insulinemic control and serum lipids profile are potential negative effects related to consumption of CLA mixture. However the safety of this CLA mixture is controversial and in some countries the CLA usage as food supplement is not authorized. Synthetic supplements of conjugated linoleic acid (CLA) containing 50:50 mixture of cis-9, trans-11 and trans-10, cis-12 CLA isomers have been commercialized in some places for reducing body fat. Department of Biology, Federal University of Juiz de Foraĭepartment of Nutrition, Federal University of Juiz de Foraĭepartment of Pharmaceutical Sciences, Federal University of Juiz de Foraĭepartment of Physiological Sciences, Roberto Alcantara Gomes Institute of Biology, State University of Rio de Janeiroĭepartment of Parasitology, Microbiology and Immunology, Federal University of Juiz de Fora
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